Rheumatoid Arthritis-Associated MicroRNA-155 Targets SOCS1 and Upregulates TNF-α and IL-1β in PBMCs

Rheumatoid Arthritis-Associated MicroRNA-155 Targets SOCS1 and Upregulates TNF-α and IL-1β in PBMCs

miR-155 plays a crucial role in proinflammatory activation. This study was carried out to assess the association of abnormal expression of miR-155 in peripheral blood of patients with Rheumatoid arthritis with the expression of TNF-α and IL-1β. Release of TNF-α and IL-1β, and expression of miR-155 w...

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Bibliographic Details
Main Authors: Xiaochuan Li, Feng Tian, Fei Wang
Format: Article
Language:English
Published: MDPI AG 2013-12-01
Series:International Journal of Molecular Sciences
Subjects:
miR-155
rheumatoid arthritis
TNF-α and IL-1β
SOCS1
Online Access:http://www.mdpi.com/1422-0067/14/12/23910

Internet

http://www.mdpi.com/1422-0067/14/12/23910

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