Oxidative Phosphorylation—an Update on a New, Essential Target Space for Drug Discovery in <i>Mycobacterium tuberculosis</i>

New drugs with new mechanisms of action are urgently required to tackle the global tuberculosis epidemic. Following the FDA-approval of the ATP synthase inhibitor bedaquiline (Sirturo<sup>®</sup>), energy metabolism has become the subject of intense focus as a novel pathway to exploit fo...

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Bibliographic Details
Main Authors: Caroline Shi-Yan Foo, Kevin Pethe, Andréanne Lupien
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/10/7/2339