A novel mutation in the maternally imprinted PEG3 domain results in a loss of MIMT1 expression and causes abortions and stillbirths in cattle (Bos taurus).

Congenital malformations resulting in late abortions and stillbirths affect the economic wellbeing of producers and the welfare of cattle in breeding programs. An extremely high incidence of stillbirths of "half-sized" calves of normal karyotype and uninflated lungs was diagnosed in the pr...

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Main Authors: Krzysztof Flisikowski, Heli Venhoranta, Joanna Nowacka-Woszuk, Stephanie D McKay, Antti Flyckt, Juhani Taponen, Robert Schnabel, Hermann Schwarzenbacher, Izabela Szczerbal, Hannes Lohi, Ruedi Fries, Jeremy F Taylor, Marek Switonski, Magnus Andersson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21152099/pdf/?tool=EBI