SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate

Transcription factors NANOG, OCT4, and SOX2 regulate self-renewal and pluripotency in human embryonic stem (hES) cells; however, their expression profiles during early differentiation of hES cells are unclear. In this study, we used multiparameter flow cytometric assay to detect all three transcript...

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Bibliographic Details
Main Authors: Ade Kallas, Martin Pook, Annika Trei, Toivo Maimets
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2014/298163