SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate

SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate

Transcription factors NANOG, OCT4, and SOX2 regulate self-renewal and pluripotency in human embryonic stem (hES) cells; however, their expression profiles during early differentiation of hES cells are unclear. In this study, we used multiparameter flow cytometric assay to detect all three transcript...

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Bibliographic Details
Main Authors:	Ade Kallas, Martin Pook, Annika Trei, Toivo Maimets
Format:	Article
Language:	English
Published:	Hindawi Limited 2014-01-01
Series:	Stem Cells International
Online Access:	http://dx.doi.org/10.1155/2014/298163

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