Constituents of the Roots and Leaves of Ekebergia capensis and Their Potential Antiplasmodial and Cytotoxic Activities

Constituents of the Roots and Leaves of Ekebergia capensis and Their Potential Antiplasmodial and Cytotoxic Activities

A new triterpenoid, 3-oxo-12β-hydroxy-oleanan-28,13β-olide (1), and six known triterpenoids 2–7 were isolated from the root bark of Ekebergia capensis, an African medicinal plant. A limonoid 8 and two glycoflavonoids 9–10 were found in its leaves. The metabolites were identified by NMR and MS analys...

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Bibliographic Details
Main Authors: Beatrice N. Irungu, Jennifer A. Orwa, Amra Gruhonjic, Paul A. Fitzpatrick, Göran Landberg, Francis Kimani, Jacob Midiwo, Máté Erdélyi, Abiy Yenesew
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Molecules
Subjects:
Ekebergia capensis
tritepenoid
antiplasmodial
cytotoxicity
Vero
4T1
HEp2
MDA-MB-231
3-oxo-12β-hydroxy-oleanan-28,13β-olide
Online Access:http://www.mdpi.com/1420-3049/19/9/14235

Internet

http://www.mdpi.com/1420-3049/19/9/14235

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