Impairing the maintenance of germinative cells in Echinococcus multilocularis by targeting Aurora kinase.

<h4>Background</h4>The tumor-like growth of the metacestode larvae of the tapeworm E. multilocularis causes human alveolar echinococcosis, a severe disease mainly affecting the liver. The germinative cells, a population of adult stem cells, are crucial for the larval growth and developme...

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Bibliographic Details
Main Authors: Zhe Cheng, Fan Liu, Huimin Tian, Zhijian Xu, Xiaoli Chai, Damin Luo, Yanhai Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007425