Involvement of hippocampal AMPA glutamate receptor changes and the cAMP/protein kinase A/CREB-P signalling pathway in memory consolidation of an avoidance task in rats

Involvement of hippocampal AMPA glutamate receptor changes and the cAMP/protein kinase A/CREB-P signalling pathway in memory consolidation of an avoidance task in rats

Training in step-down inhibitory avoidance (0.3-mA footshock) is followed by biochemical changes in rat hippocampus that strongly suggest an involvement of quantitative changes in glutamate AMPA receptors, followed by changes in the dopamine D1 receptor/cAMP/protein kinase A (PKA)/CREB-P signalling...

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Bibliographic Details
Main Authors: R. Bernabeu, M. Cammarota, I. Izquierdo, J.H. Medina
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1997-08-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
glutamate AMPA receptors
cAMP/PKA/CREB pathway
memory formation
rat hippocampus
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000800008

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000800008

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