HDL subclass proteomic analysis and functional implication of protein dynamic change during HDL maturation

Recent clinical trials reported that increasing high-density lipoprotein-cholesterol (HDL-C) levels does not improve cardiovascular outcomes. We hypothesize that HDL proteome dynamics determine HDL cardioprotective functions. In this study, we characterized proteome profiles in HDL subclasses and es...

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Bibliographic Details
Main Authors: Yuling Zhang, Scott M. Gordon, Hang Xi, Seungbum Choi, Merlin Abner Paz, Runlu Sun, William Yang, Jason Saredy, Mohsin Khan, Alan Thomas Remaley, Jing-Feng Wang, Xiaofeng Yang, Hong Wang
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719304604