Do sputum or circulating blood samples reflect the pulmonary transcriptomic differences of COPD patients? A multi-tissue transcriptomic network META-analysis

Do sputum or circulating blood samples reflect the pulmonary transcriptomic differences of COPD patients? A multi-tissue transcriptomic network META-analysis

Abstract Background Previous studies have identified lung, sputum or blood transcriptomic biomarkers associated with the severity of airflow limitation in COPD. Yet, it is not clear whether the lung pathobiology is mirrored by these surrogate tissues. The aim of this study was to explore this questi...

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Bibliographic Details
Main Authors: Rosa Faner, Jarrett D. Morrow, Sandra Casas-Recasens, Suzanne M. Cloonan, Guillaume Noell, Alejandra López-Giraldo, Ruth Tal-Singer, Bruce E. Miller, Edwin K. Silverman, Alvar Agustí, Craig P. Hersh
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Respiratory Research
Subjects:
mRNA
Chronic bronchitis
Emphysema
Co-expression network analysis
Online Access:http://link.springer.com/article/10.1186/s12931-018-0965-y

Internet

http://link.springer.com/article/10.1186/s12931-018-0965-y

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