Cystic Fibrosis: Overview of the Current Development Trends and Innovative Therapeutic Strategies

Cystic Fibrosis (CF), an autosomal recessive genetic disease, is caused by a mutation in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). This mutation reduces the release of chloride ions (Cl<sup>−</sup>) in epithelial tissues, and hyperactivates the epi...

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Bibliographic Details
Main Authors: Fahad A. Almughem, Ahmad M. Aldossary, Essam A. Tawfik, Mohammad N. Alomary, Waleed S. Alharbi, Mohammad Y. Alshahrani, Abdullah A. Alshehri
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/12/7/616