Serious adverse events reported in placebo randomised controlled trials of oral naltrexone: a systematic review and meta-analysis

Abstract Background Naltrexone is an opioid antagonist used in many different conditions, both licensed and unlicensed. It is used at widely varying doses from 3 to 250 mg. The aim of this review was to extensively evaluate the safety of oral naltrexone by examining the risk of serious adverse event...

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Bibliographic Details
Main Authors: Monica Bolton, Alex Hodkinson, Shivani Boda, Alan Mould, Maria Panagioti, Sarah Rhodes, Lisa Riste, Harm van Marwijk
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Medicine
Subjects:
LDN
Online Access:http://link.springer.com/article/10.1186/s12916-018-1242-0