Comparative Anticonvulsant Study of Epoxycarvone Stereoisomers

Comparative Anticonvulsant Study of Epoxycarvone Stereoisomers

Stereoisomers of the monoterpene epoxycarvone (EC), namely (+)-cis-EC, (−)-cis-EC, (+)-trans-EC, and (−)-trans-EC, were comparatively evaluated for anticonvulsant activity in specific methodologies. In the pentylenetetrazole (PTZ)-induced anticonvulsant test, all of the stereoisomers (at 300 mg/kg)...

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Bibliographic Details
Main Authors: Paula Regina Rodrigues Salgado, Diogo Vilar da Fonsêca, Renan Marinho Braga, Cynthia Germoglio Farias de Melo, Luciana Nalone Andrade, Reinaldo Nóbrega de Almeida, Damião Pergentino de Sousa
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Molecules
Subjects:
anticonvulsant
carvone
stereoisomers
terpene
natural products
essential oils
pentylenetetrazole
seizures
para-menthanes
enantiomers
Online Access:http://www.mdpi.com/1420-3049/20/11/19649

Internet

http://www.mdpi.com/1420-3049/20/11/19649

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