Microglial motility in Alzheimer’s disease and after Aβ42 immunotherapy: a human post-mortem study

Microglial motility in Alzheimer’s disease and after Aβ42 immunotherapy: a human post-mortem study

Abstract Microglial function is highly dependent on cell motility, with baseline motility required for homeostatic surveillance activity and directed motility to migrate towards a source of injury. Experimental evidence suggests impaired microglial motility in Alzheimer’s disease (AD) and therefore...

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Bibliographic Details
Main Authors: Diana K. Franco-Bocanegra, Bethany George, Laurie C. Lau, Clive Holmes, James A. R. Nicoll, Delphine Boche
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Acta Neuropathologica Communications
Subjects:
Human microglia
Cell motility
Alzheimer’s disease
Aβ-immunotherapy
Neuroinflammation
Online Access:http://link.springer.com/article/10.1186/s40478-019-0828-x

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http://link.springer.com/article/10.1186/s40478-019-0828-x

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