Establishment of Nephrin Reporter Mice and Use for Chemical Screening.

Establishment of Nephrin Reporter Mice and Use for Chemical Screening.

Nephrin is a critical component of glomerular filtration barrier, which is important to maintain glomerular structure and avoid proteinuria. Downregulation of nephrin expression is commonly observed at early stage of glomerular disorders, suggesting that methods to increase nephrin expression in pod...

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Bibliographic Details
Main Authors: Junichi Tsuchida, Taiji Matsusaka, Masato Ohtsuka, Hiromi Miura, Yukiko Okuno, Katsuhiko Asanuma, Takahiko Nakagawa, Motoko Yanagita, Kiyoshi Mori
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4928931?pdf=render

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http://europepmc.org/articles/PMC4928931?pdf=render

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