Circadian Differences in the Contribution of the Brain Renin-Angiotensin System in Genetically Hypertensive Mice

Objective: Genetically hypertensive BPH/2J mice are recognized as a neurogenic model of hypertension, primarily based on sympathetic overactivity and greater neuronal activity in cardiovascular regulatory brain regions. Greater activity of the central renin angiotensin system (RAS) and reactive oxyg...

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Bibliographic Details
Main Authors: Kristy L. Jackson, Francine Z. Marques, Kyungjoon Lim, Pamela J. Davern, Geoffrey A. Head
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00231/full