Circadian Differences in the Contribution of the Brain Renin-Angiotensin System in Genetically Hypertensive Mice
Objective: Genetically hypertensive BPH/2J mice are recognized as a neurogenic model of hypertension, primarily based on sympathetic overactivity and greater neuronal activity in cardiovascular regulatory brain regions. Greater activity of the central renin angiotensin system (RAS) and reactive oxyg...
Main Authors: | Kristy L. Jackson, Francine Z. Marques, Kyungjoon Lim, Pamela J. Davern, Geoffrey A. Head |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-03-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fphys.2018.00231/full |
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