Membrane connectivity estimated by digital image analysis of HER2 immunohistochemistry is concordant with visual scoring and fluorescence in situ hybridization results: algorithm evaluation on breast cancer tissue microarrays

<p>Abstract</p> <p>Introduction</p> <p>The human epidermal growth factor receptor 2 (HER2) is an established biomarker for management of patients with breast cancer. While conventional testing of HER2 protein expression is based on semi-quantitative visual scoring of th...

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Bibliographic Details
Main Authors: Jarmalaite Sonata, Ostapenko Valerijus, Dasevicius Darius, Laurinaviciene Aida, Lazutka Juozas, Laurinavicius Arvydas
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Diagnostic Pathology
Online Access:http://www.diagnosticpathology.org/content/6/1/87