An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways

The CD8 T cell response to Zika virus is known to be a critical component of the host immune response to infection. Here the authors show a Zika virus isolate specific disruption of antigen processing that impacts the host response and impairs viral clearance providing evidence of isolate specific i...

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Bibliographic Details
Main Authors: Ryan D. Pardy, Stefanie F. Valbon, Brendan Cordeiro, Connie M. Krawczyk, Martin J. Richer
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24340-0