A probabilistic model to predict clinical phenotypic traits from genome sequencing.

Genetic screening is becoming possible on an unprecedented scale. However, its utility remains controversial. Although most variant genotypes cannot be easily interpreted, many individuals nevertheless attempt to interpret their genetic information. Initiatives such as the Personal Genome Project (P...

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Bibliographic Details
Main Authors: Yun-Ching Chen, Christopher Douville, Cheng Wang, Noushin Niknafs, Grace Yeo, Violeta Beleva-Guthrie, Hannah Carter, Peter D Stenson, David N Cooper, Biao Li, Sean Mooney, Rachel Karchin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4154636?pdf=render