Enriched Bone Marrow Derived Disseminated Neuroblastoma Cells Can Be a Reliable Source for Gene Expression Studies-A Validation Study.

Metastases in the bone marrow (BM) in form of disseminated tumor cells (DTCs) are frequent events at diagnosis and also at relapse in high-risk neuroblastoma patients. The frequently highly diluted occurrence of DTCs requires adequate enrichment strategies to enable their detailed characterization....

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Bibliographic Details
Main Authors: Fikret Rifatbegovic, M Reza Abbasi, Sabine Taschner-Mandl, Maximilian Kauer, Andreas Weinhäusel, Rupert Handgretinger, Peter F Ambros
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4567134?pdf=render