Feasibility of transdermal transport of atenolol by combination of iontophoresis and oleic acid pretreatment

Atenolol has a low oral bioavailability and a short elimination half-life. Therefore, alternative route and delivery system is important. Transdermal iontophoresis, i.e. a systemic drug delivery via the skin, implementing a low intensity of electrical current, is on...

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Bibliographic Details
Main Authors: Akhmad Kharis Nugroho, Arief Rahman Hakim, Marlyn Dian Laksitorini, Fajar Rakhmatullah, Eny Masruriati
Format: Article
Language:English
Published: Universitas Gadjah Mada 2011-01-01
Series:Indonesian Journal of Pharmacy
Subjects:
Online Access:http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/595/470