8-Gingerol Ameliorates Myocardial Fibrosis by Attenuating Reactive Oxygen Species, Apoptosis, and Autophagy via the PI3K/Akt/mTOR Signaling Pathway

8-Gingerol Ameliorates Myocardial Fibrosis by Attenuating Reactive Oxygen Species, Apoptosis, and Autophagy via the PI3K/Akt/mTOR Signaling Pathway

8-gingerol (8-Gin) is the series of phenolic substance that is extracted from ginger. Although many studies have revealed that 8-Gin has multiple pharmacological properties, the possible underlying mechanisms of 8-Gin against myocardial fibrosis (MF) remains unclear. The study examined the exact rol...

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Bibliographic Details
Main Authors: Yucong Xue, Muqing Zhang, Miaomiao Liu, Yu Liu, Li Li, Xue Han, Zhenqing Sun, Li Chu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
8-gingerol
myocardial fibrosis
reactive oxygen species
apoptosis
autophagy
PI3K/Akt/mTOR signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.711701/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.711701/full

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