Age at diagnosis, but not HPV type, is strongly associated with clinical course in recurrent respiratory papillomatosis.

<h4>Background</h4>Recurrent Respiratory Papillomatosis (RRP) is a rare disease characterized by the growth of papillomas in the airway and especially the larynx. The clinical course is highly variable among individuals and there is poor understanding of the factors that drive an aggress...

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Main Authors: Farrel J Buchinsky, William L Valentino, Nicole Ruszkay, Evan Powell, Craig S Derkay, Riaz Y Seedat, Virgilijus Uloza, Frederik G Dikkers, David E Tunkel, Sukgi S Choi, Anthony J Mortelliti, Paolo Campisi, Juan C Ospina, Adam J Donne, Robert T Sataloff, Stephen F Conley, John E McClay, Ellen M Friedman, Lisa Elden, Dale A Tylor, Clark A Rosen, Libby J Smith, Graeme J Copley, David E Karas, John M Schweinfurth, Charles M Myer, Brian J Wiatrak, Joseph E Dohar, Steven E Sobol, Robert W Bastian, Richard J H Smith, Marshall E Smith, Abebe M Wassie, James C Post, Garth D Ehrlich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0216697