CD49f(high) cells retain sphere-forming and tumor-initiating activities in human gastric tumors.

Identification of gastric tumor-initiating cells (TICs) is essential to explore new therapies for gastric cancer patients. There are reports that gastric TICs can be identified using the cell surface marker CD44 and that they form floating spheres in culture, but we could not obtain consistent resul...

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Bibliographic Details
Main Authors: Hiroshi Fukamachi, Hyang Sook Seol, Shu Shimada, Chikako Funasaka, Kanako Baba, Ji Hun Kim, Young Soo Park, Mi Jeung Kim, Keiji Kato, Mikito Inokuchi, Hiroshi Kawachi, Jeong Hwan Yook, Yoshinobu Eishi, Kazuyuki Kojima, Woo Ho Kim, Se Jin Jang, Yasuhito Yuasa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3756075?pdf=render