Phenotypic modulation of human articular chondrocytes by bistratene A
Chondrocytes undergo phenotypic alterations following extended periods in monolayer culture, i.e., they become bipolar and flattened, proliferate, and synthesise type I as opposed to type II collagen. This process has been termed chondrocyte dedifferentiation. Bistratene A is a macrolide polyether t...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
AO Research Institute Davos
2002-06-01
|
| Series: | European Cells & Materials |
| Online Access: | http://www.ecmjournal.org/journal/papers/vol003/vol003a02.php |