1400W, a highly selective inducible nitric oxide synthase inhibitor is a potential disease modifier in the rat kainate model of temporal lobe epilepsy

1400W, a highly selective inducible nitric oxide synthase inhibitor is a potential disease modifier in the rat kainate model of temporal lobe epilepsy

Status epilepticus (SE) initiates epileptogenesis to transform normal brain to epileptic state which is characterized by spontaneous recurrent seizures (SRS). Prior to SRS, progressive changes occur in the brain soon after SE, for example, loss of blood–brain barrier (BBB) integrity, neuronal hyper-...

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Bibliographic Details
Main Authors: Sreekanth Puttachary, Shaunik Sharma, Saurabh Verma, Yang Yang, Marson Putra, Achala Thippeswamy, Diou Luo, Thimmasettappa Thippeswamy
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Neurobiology of Disease
Subjects:
Neuroinflammation
Neurodegeneration
Blood–brain barrier
Serum albumin
Kir 4.1
GLT-1
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116301073

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http://www.sciencedirect.com/science/article/pii/S0969996116301073

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