Measles Vaccines Designed for Enhanced CD8<sup>+</sup> T Cell Activation

Measles Vaccines Designed for Enhanced CD8<sup>+</sup> T Cell Activation

Priming and activation of CD8<sup>+</sup> T cell responses is crucial to achieve anti-viral and anti-tumor immunity. Live attenuated measles vaccine strains have been used successfully for immunization for decades and are currently investigated in trials of oncolytic virotherapy. The ava...

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Bibliographic Details
Main Authors: Elena Busch, Kristina D. Kubon, Johanna K. M. Mayer, Gemma Pidelaserra-Martí, Jessica Albert, Birgit Hoyler, Johannes P. W. Heidbuechel, Kyle B. Stephenson, Brian D. Lichty, Wolfram Osen, Stefan B. Eichmüller, Dirk Jäger, Guy Ungerechts, Christine E. Engeland
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Viruses
Subjects:
measles
vaccination
cd8<sup>+</sup> t cell activation
oncolytic virus
t cell priming
cancer immunotherapy
Online Access:https://www.mdpi.com/1999-4915/12/2/242

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https://www.mdpi.com/1999-4915/12/2/242

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