SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts.

SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts.

Vaccines are urgently needed to combat the global coronavirus disease 2019 (COVID-19) pandemic, and testing of candidate vaccines in an appropriate non-human primate (NHP) model is a critical step in the process. Infection of African green monkeys (AGM) with a low passage human isolate of SARS-CoV-2...

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Bibliographic Details
Main Authors: Amy L Hartman, Sham Nambulli, Cynthia M McMillen, Alexander G White, Natasha Louise Tilston-Lunel, Joseph R Albe, Emily Cottle, Matthew D Dunn, L James Frye, Theron H Gilliland, Emily L Olsen, Katherine J O'Malley, Madeline M Schwarz, Jaime A Tomko, Reagan C Walker, Mengying Xia, Matthew S Hartman, Edwin Klein, Charles A Scanga, JoAnne L Flynn, William B Klimstra, Anita K McElroy, Douglas S Reed, W Paul Duprex
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008903

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https://doi.org/10.1371/journal.ppat.1008903

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