Expression of Phosphorylated BRD4 Is Markedly Associated with the Activation Status of the PP2A Pathway and Shows AStrong Prognostic Value in Triple Negative Breast Cancer Patients

Expression of Phosphorylated BRD4 Is Markedly Associated with the Activation Status of the PP2A Pathway and Shows AStrong Prognostic Value in Triple Negative Breast Cancer Patients

The bromodomain-containing protein 4 (BRD4), a member of the bromodomain and extra-terminal domain (BET) protein family, has emerged in the last years as a promising molecular target in many tumors including breast cancer. The triple negative breast cancer (TNBC) represents the molecular subtype wit...

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Bibliographic Details
Main Authors: Marta Sanz-Álvarez, Ion Cristóbal, Melani Luque, Andrea Santos, Sandra Zazo, Juan Madoz-Gúrpide, Cristina Caramés, Cheng-Ming Chiang, Jesús García-Foncillas, Pilar Eroles, Joan Albanell, Federico Rojo
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
pBRD4
SET
PP2A
prognosis
triple negative breast cancer
Online Access:https://www.mdpi.com/2072-6694/13/6/1246

Internet

https://www.mdpi.com/2072-6694/13/6/1246

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