Phosphorylation of ERK5 on Thr732 is associated with ERK5 nuclear localization and ERK5-dependent transcription.

Phosphorylation of ERK5 on Thr732 is associated with ERK5 nuclear localization and ERK5-dependent transcription.

Extracellular signal-regulated kinases (ERKs) play critical roles in numerous cellular processes, including proliferation and differentiation. ERK5 contains a kinase domain at the N-terminal, and the unique extended C-terminal includes multiple autophosphorylation sites that enhance ERK5-dependent t...

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Bibliographic Details
Main Authors: Takuto Honda, Yutaro Obara, Arata Yamauchi, Anthony D Couvillon, Justin J Mason, Kuniaki Ishii, Norimichi Nakahata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4331489?pdf=render

Internet

http://europepmc.org/articles/PMC4331489?pdf=render

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