Endoplasmic reticulum stress enhances the antigen-specific T cell immune responses and therapeutic antitumor effects generated by therapeutic HPV vaccines

Endoplasmic reticulum stress enhances the antigen-specific T cell immune responses and therapeutic antitumor effects generated by therapeutic HPV vaccines

Abstract Background Endoplasmic reticulum stress has a profound effect on cancer cell proliferation and survival, and also has the capacity to activate cells of the adaptive immune system. Multimodal treatment methods that utilize and combine conventional cancer therapies with antigen-specific immun...

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Bibliographic Details
Main Authors: Sung Yong Lee, Jee Youn Oh, Tae Heung Kang, Hyun Seock Shin, Max A. Cheng, Emily Farmer, T.-C. Wu, Chien-Fu Hung
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Journal of Biomedical Science
Subjects:
HPV
HPV16
Therapeutic HPV vaccine
pcDNA3-CRT/E7
3-bromopyruvate
Endoplasmic reticulum stress
Online Access:http://link.springer.com/article/10.1186/s12929-019-0536-7

Internet

http://link.springer.com/article/10.1186/s12929-019-0536-7

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