MethHaplo: combining allele-specific DNA methylation and SNPs for haplotype region identification

Abstract Background DNA methylation is an important epigenetic modification that plays a critical role in most eukaryotic organisms. Parental alleles in haploid genomes may exhibit different methylation patterns, which can lead to different phenotypes and even different therapeutic and drug response...

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Bibliographic Details
Main Authors: Qiangwei Zhou, Ze Wang, Jing Li, Wing-Kin Sung, Guoliang Li
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Bioinformatics
Subjects:
SNP
Online Access:http://link.springer.com/article/10.1186/s12859-020-03798-7