Type I Interferons Regulate Immune Responses in Humans with Blood-Stage Plasmodium falciparum Infection

Type I Interferons Regulate Immune Responses in Humans with Blood-Stage Plasmodium falciparum Infection

The development of immunoregulatory networks is important to prevent disease. However, these same networks allow pathogens to persist and reduce vaccine efficacy. Here, we identify type I interferons (IFNs) as important regulators in developing anti-parasitic immunity in healthy volunteers infected...

Full description

Bibliographic Details
Main Authors: Marcela Montes de Oca, Rajiv Kumar, Fabian de Labastida Rivera, Fiona H. Amante, Meru Sheel, Rebecca J. Faleiro, Patrick T. Bunn, Shannon E. Best, Lynette Beattie, Susanna S. Ng, Chelsea L. Edwards, Glen M. Boyle, Ric N. Price, Nicholas M. Anstey, Jessica R. Loughland, Julie Burel, Denise L. Doolan, Ashraful Haque, James S. McCarthy, Christian R. Engwerda
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Cell Reports
Subjects:
malaria
type I interferons
CD4+ T cells
immune regulation
Tr1 cells
Th1 cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716312207

Internet

http://www.sciencedirect.com/science/article/pii/S2211124716312207

Similar Items