TRIM52 up-regulation in hepatocellular carcinoma cells promotes proliferation, migration and invasion through the ubiquitination of PPM1A

TRIM52 up-regulation in hepatocellular carcinoma cells promotes proliferation, migration and invasion through the ubiquitination of PPM1A

Abstract Background Many tripartite motif (TRIM) family proteins have been reported to be of great importance in the initiation and progression in hepatocellular carcinoma (HCC). However, the biological role and regulatory mechanism of tripartite motif containing 52 (TRIM52) in HCC development and p...

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Bibliographic Details
Main Authors: Yi Zhang, Ran Tao, Shan-Shan Wu, Cui-Cui Xu, Jie-Ling Wang, Jie Chen, Yong-Sheng Yu, Zheng-Hao Tang, Xiao-Hua Chen, Guo-Qing Zang
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Hepatocellular carcinoma
TRIM52
PPM1A
Ubiquitination
Online Access:http://link.springer.com/article/10.1186/s13046-018-0780-9

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http://link.springer.com/article/10.1186/s13046-018-0780-9

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