Sex-Based Mhrt Methylation Chromatinizes MeCP2 in the Heart
Summary: In the heart, primary microRNA-208b (pri-miR-208b) and Myheart (Mhrt) are long non-coding RNAs (lncRNAs) encoded by the cardiac myosin heavy chain genes. Although preclinical studies have shown that lncRNAs regulate gene expression and are protective for pathological hypertrophy, the mechan...
Main Authors: | Harikrishnan K.N., Jun Okabe, Prabhu Mathiyalagan, Abdul Waheed Khan, Sameer A. Jadaan, Gulcan Sarila, Mark Ziemann, Ishant Khurana, Scott S. Maxwell, Xiao-Jun Du, Assam El-Osta |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2019-07-01
|
Series: | iScience |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004219302147 |
Similar Items
-
MeCP2 and Chromatin Compartmentalization
by: Annika Schmidt, et al.
Published: (2020-04-01) -
MeCP2 and its interaction with DNA and chromatin
by: Galvão, Teca Calcagno
Published: (2001) -
DNA and chromatin binding by the methyl-CpG-binding protein, MeCP2
by: Goddard, C.
Published: (2003) -
SAHA attenuates Takotsubo-like myocardial injury by targeting an epigenetic Ac/Dc axis
by: Ishant Khurana, et al.
Published: (2021-04-01) -
Circadian cycle-dependent MeCP2 and brain chromatin changes.
by: Alexia Martínez de Paz, et al.
Published: (2015-01-01)