Determination of apramycin in oral soluble powder by a HPLC method using pre-column derivatization with o-phthalaldehyde and UV detection

A high-performance liquid chromatographic method employing pre-column derivatization with o-phthalaldehyde (OPA) and 2-mercaptoacetic acid was developed for the determination of apramycin, an aminoglycoside antibiotic used in veterinary medicine, in the oral soluble powder form. The chromatographic...

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Bibliographic Details
Main Authors: Elisabete de Almeida Barbosa Antunes, Felipe Rebello Lourenço, Terezinha de Jesus Andreoli Pinto
Format: Article
Language:English
Published: Universidade de São Paulo 2011-06-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
OPA
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000200007