Wnt/β-catenin signaling in cancers and targeted therapies

Abstract Wnt/β-catenin signaling has been broadly implicated in human cancers and experimental cancer models of animals. Aberrant activation of Wnt/β-catenin signaling is tightly linked with the increment of prevalence, advancement of malignant progression, development of poor prognostics, and even...

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Bibliographic Details
Main Authors: Fanyuan Yu, Changhao Yu, Feifei Li, Yanqin Zuo, Yitian Wang, Lin Yao, Chenzhou Wu, Chenglin Wang, Ling Ye
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00701-5