Synthesis, photochemical and electrochemical studies on triphenyltin(IV) derivative of (Z)-4-(4-cyanophenylamino)-4-oxobut-2-enoic acid for its binding with DNA: Biological interpretation

Synthesis, photochemical and electrochemical studies on triphenyltin(IV) derivative of (Z)-4-(4-cyanophenylamino)-4-oxobut-2-enoic acid for its binding with DNA: Biological interpretation

(Z)-4-(4-cyanophenylamino)-4-oxobut-2-enoic acid (LH) and its new triphenyltin (IV) derivative (Ph3SnL) were synthesized and further investigated for their binding with ds.DNA under physiological conditions {pH: 4.7 (stomach); 7.4 (blood), 37 °C} using UV–Visible/fluorescence spectroscopy, cyclic vo...

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Bibliographic Details
Main Authors: Nasima Arshad, Moazzam H. Bhatti, Shahid Iqbal Farooqi, Samreen Saleem, Bushra Mirza
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Arabian Journal of Chemistry
Subjects:
Triorganotins
UV–Visible spectroscopy
Fluorescence spectroscopy
Cyclic voltammetry
DNA binding
Bioactivities
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535214001804

Internet

http://www.sciencedirect.com/science/article/pii/S1878535214001804

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