TGF-beta1 does not induce senescence of multipotent mesenchymal stromal cells and has similar effects in early and late passages.

TGF-beta1 does not induce senescence of multipotent mesenchymal stromal cells and has similar effects in early and late passages.

Transforming growth factor-beta 1 (TGF-β1) stimulates a broad range of effects which are cell type dependent, and it has been suggested to induce cellular senescence. On the other hand, long-term culture of multipotent mesenchymal stromal cells (MSCs) has a major impact on their cellular physiology...

Full description

Bibliographic Details
Main Authors: Gudrun Walenda, Khalid Abnaof, Sylvia Joussen, Steffen Meurer, Hubert Smeets, Björn Rath, Kurt Hoffmann, Holger Fröhlich, Martin Zenke, Ralf Weiskirchen, Wolfgang Wagner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3798389?pdf=render

Internet

http://europepmc.org/articles/PMC3798389?pdf=render

Similar Items