Broad cross-reactive IgG responses elicited by adjuvanted vaccination with recombinant influenza hemagglutinin (rHA) in ferrets and mice.

Annual immunization against influenza virus is a large international public health effort. Accumulating evidence suggests that antibody mediated cross-reactive immunity against influenza hemagglutinin (HA) strongly correlates with long-lasting cross-protection against influenza virus strains that di...

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Bibliographic Details
Main Authors: Jiong Wang, Shannon P Hilchey, Marta DeDiego, Sheldon Perry, Ollivier Hyrien, Aitor Nogales, Jessica Garigen, Fatima Amanat, Nelson Huertas, Florian Krammer, Luis Martinez-Sobrido, David J Topham, John J Treanor, Mark Y Sangster, Martin S Zand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5894995?pdf=render