Heme Oxygenase-2 Localizes to Mitochondria and Regulates Hypoxic Responses in Hepatocytes

Hypoxia occurs as a part of multiple disease states, including hemorrhagic shock. Adaptive responses occur within the cell to limit the consequences of hypoxia. This includes changes in mitochondrial respiration, stress-induced cell signaling, and gene expression that is regulated by hypoxia inducib...

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Bibliographic Details
Main Authors: Paul K. Waltz, Benjamin Kautza, Jason Luciano, Mitch Dyer, Donna Beer Stolz, Patricia Loughran, Matthew D. Neal, Jason L. Sperry, Matthew R. Rosengart, Brian S. Zuckerbraun
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/2021645