Integrating Clinical and Genomic Analyses of Hippocampal-Prefrontal Circuit Disorder in Depression

Integrating Clinical and Genomic Analyses of Hippocampal-Prefrontal Circuit Disorder in Depression

Major depressive disorder (MDD) is a prevalent, devastating and recurrent mental disease. Hippocampus (HIP)-prefrontal cortex (PFC) neural circuit abnormalities have been confirmed to exist in MDD; however, the gene-related molecular features of this circuit in the context of depression remain uncle...

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Bibliographic Details
Main Authors: Naijun Yuan, Kairui Tang, Xiaoli Da, Hua Gan, Liangliang He, Xiaojuan Li, Qingyu Ma, Jiaxu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Genetics
Subjects:
depression
hippocampus-prefrontal circuit
integrative approaches
gene expression
clinical state
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.565749/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2020.565749/full

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