Accurate detection of m6A RNA modifications in native RNA sequences

Accurate detection of m6A RNA modifications in native RNA sequences

We currently lack generic methods to map RNA modifications across the entire transcriptome. Here, the authors demonstrate that m6A RNA modifications can be detected with high accuracy using nanopore direct RNA sequencing.

Bibliographic Details
Main Authors: Huanle Liu, Oguzhan Begik, Morghan C. Lucas, Jose Miguel Ramirez, Christopher E. Mason, David Wiener, Schraga Schwartz, John S. Mattick, Martin A. Smith, Eva Maria Novoa
Format: Article
Language:English
Published: Nature Publishing Group 2019-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11713-9

Internet

https://doi.org/10.1038/s41467-019-11713-9

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