TRAIL dependent fratricidal killing of gp120 primed hepatocytes by HCV core expressing hepatocytes.

The mechanism by which HIV and HCV cooperatively accelerate hepatocyte damage is not clearly understood; however, each virus affects the TRAIL: TRAIL-receptor system. We, therefore, questioned whether the independent effects of HCV and HIV combine to synergistically result in TRAIL dependent hepatoc...

Full description

Bibliographic Details
Main Authors: Stacey A Rizza, Kishore B Challagundla, Sekar Natesampillai, Gary D Bren, Jaromir Sykora, Henning Walczak, Andrew D Badley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3215710?pdf=render