Branched-chain amino acids and l-carnitine attenuate lipotoxic hepatocellular damage in rat cirrhotic liver

Branched-chain amino acids and l-carnitine attenuate lipotoxic hepatocellular damage in rat cirrhotic liver

Branched-chain amino acids (BCAA) reverse malnutrition and l-carnitine leads to the reduction of hyperammonemia and muscle cramps in cirrhotic patients. BCAA and l-carnitine are involved in glucose and fatty acid metabolism, however their mechanistic activity in cirrhotic liver is not fully understo...

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Bibliographic Details
Main Authors: Yasuyuki Tamai, Zhen Chen, Yue Wu, Jun Okabe, Yoshinao Kobayashi, Hitoshi Chiba, Shu-Ping Hui, Akiko Eguchi, Motoh Iwasa, Masaaki Ito, Yoshiyuki Takei
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
L-carnitine
Branched-chain amino acids
Cirrhosis
Lipid peroxides
Cardiolipins
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220313743

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http://www.sciencedirect.com/science/article/pii/S0753332220313743

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