A DNA damage-induced, SOS-independent checkpoint regulates cell division in Caulobacter crescentus.

Cells must coordinate DNA replication with cell division, especially during episodes of DNA damage. The paradigm for cell division control following DNA damage in bacteria involves the SOS response where cleavage of the transcriptional repressor LexA induces a division inhibitor. However, in Cauloba...

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Bibliographic Details
Main Authors: Joshua W Modell, Tracy K Kambara, Barrett S Perchuk, Michael T Laub
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4211646?pdf=render