GlyCAM1 negatively regulates monocyte entry into the optic nerve head and contributes to radiation-based protection in glaucoma

GlyCAM1 negatively regulates monocyte entry into the optic nerve head and contributes to radiation-based protection in glaucoma

Abstract Background We previously reported a profound long-term neuroprotection subsequent to a single radiation-therapy in the DBA/2J mouse model of glaucoma. This neuroprotection prevents entry of monocyte-like immune cells into the optic nerve head during glaucoma. Gene expression studies in radi...

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Bibliographic Details
Main Authors: Pete A. Williams, Catherine E. Braine, Nicole E. Foxworth, Kelly E. Cochran, Simon W. M. John
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Journal of Neuroinflammation
Subjects:
Glaucoma
GlyCAM1
Monocytes
Retinal ganglion cell
Radiation therapy
Online Access:http://link.springer.com/article/10.1186/s12974-017-0868-8

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http://link.springer.com/article/10.1186/s12974-017-0868-8

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