Sodium Butyrate and Indole-3-propionic Acid Prevent the Increase of Cytokines and Kynurenine Levels in LPS-induced Human Primary Astrocytes

The crosstalk between central nervous system (CNS) and gut microbiota plays key roles in neuroinflammation and chronic immune activation that are common features of all neurodegenerative diseases. Imbalance in the microbiota can lead to an increase in the intestinal permeability allowing toxins to d...

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Bibliographic Details
Main Authors: Michelle L Garcez, Vanessa X Tan, Benjamin Heng, Gilles J Guillemin
Format: Article
Language:English
Published: SAGE Publishing 2020-12-01
Series:International Journal of Tryptophan Research
Online Access:https://doi.org/10.1177/1178646920978404