The Role of Vascular Endothelial Growth Factor Receptor-1 Signaling in the Recovery from Ischemia.

Vascular endothelial growth factor (VEGF) is one of the most potent angiogenesis stimulators. VEGF binds to VEGF receptor 1 (VEGFR1), inducing angiogenesis through the receptor's tyrosine kinase domain (TK), but the mechanism is not well understood. We investigated the role of VEGFR1 tyrosine k...

Full description

Bibliographic Details
Main Authors: Hideki Amano, Shintaro Kato, Yoshiya Ito, Koji Eshima, Fumihiro Ogawa, Ryo Takahashi, Kazuki Sekiguchi, Hideaki Tamaki, Hiroyuki Sakagami, Masabumi Shibuya, Masataka Majima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4489890?pdf=render